Results/Conclusions The USDA listed nearly 40 forest medicinal plant species with potential commercial use for treating common colds to complex diseases such as cancers. Out of these, ginseng (Panax ginseng), goldenseal (Hydrastis canadensis), black (Actea racemosa L) and blue (Caulophyllum thalictroides) cohosh , skull cap (Scutellaria spp.), lobelia (Lobelia inflate), wild strawberry (Fragaria virginiana), spice bush (Lindera benzoin), Indian hemp (Cannabis sativa), coltsfoot (Tussilago Farfara), trillium (Trillium spp.), heal-all (Prunella vulgaris), jewel weed (Impatiens capensis), snakeroot (Polygala senega), chestnut (Castanea vesca), white fringe tree (Chionanthus virginicus), white colic root (Aletris farinose), and hawthorn (Crataegus oxyacantha) have been identified as having high to very high market demand. Forest farming with goldenseal will be presented as a case study to illustrate forest farming in southern forests., jewel weed (), snakeroot (), chestnut (), white fringe tree (), white colic root (), and hawthorn () have been identified as having high to very high market demand. Forest farming with goldenseal will be presented as a case study to illustrate forest farming in southern forests.