Predicting the future by studying little things in big places and big things in little places

How is life responding to climate change and other pressures of human civilization? This is a huge question that requires a rapid answer at local scales everywhere around the planet. To have any hope of answering this question, we need to break it into manageable parts while still extrapolating to the whole. I will show how to move back and forth from the small—such as genes within individuals or populations—to the large—such as the range of entire species and the composition of ecosystems—to make predictions about what the future biosphere might be like.